A Review of Alzheimer’s Disease Pathology across the Age Range
Dietmar Thal, PhD, describes the pathological hallmarks of Alzheimer’s disease, including amyloid beta plaques, neuritic plaques, neurofibrillary tangles, and cerebral amyloid angiopathy. He discusses the genetic influence on Alzheimer’s disease pathology and highlights the differences in Alzheimer’s disease pathology according to age of symptom onset. Philip Scheltens then describes the ultimate diagnosis of the patient case study and summarizes the differences between typical and atypical Alzheimer’s disease and familial and non-familial early-onset Alzheimer’s disease.
Key Learning Objectives for Biogen’s AAT-AD/PD 2020 Symposium:
- Understand the importance of an early diagnosis of Alzheimer’s disease
- Assess the current healthcare system readiness for a paradigm shift to early diagnosis
- Gain insights on how cognitive assessment tools and imaging biomarkers can be used to distinguish between different subtypes of Alzheimer’s disease
- Increase understanding of the differences between the pathology of familial or sporadic early-onset and late-onset Alzheimer’s disease
Disclosure: All panelists received honoraria from Biogen for participation in this symposium.
Disclaimer: All of the information discussed today is for informational purposes only; does not constitute medical advice; and is not intended to be a substitute for independent professional medical judgment, advice, diagnosis, or treatment.